1. Corresponding Author:
    Michael T. Lotze, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA 15213. Phone: 412-623-6790; Fax: 412-623-1212; E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Why human tumors grow infiltrated by specific antitumor T cells has been a mystery attributed to negative factors released directly by the tumor or indirectly through immune intermediaries. The frequency and phenotype of myeloid-derived suppressor cells in the peripheral blood of melanoma patients and healthy donors are surprisingly similar. Clin Cancer Res; 18(19); 5157–9. ©2012 AACR.

Commentary on Gros et al., p. 5212

  • Received August 13, 2012.
  • Accepted August 16, 2012.

Melanoma Research Foundation

Donate Today

Every day the Melanoma Research Foundation works to make the fight against melanoma easier.
Your donation will help us support patients, fund research and advocate for the melanoma community.