1. Corresponding Author:
    Michael T. Lotze, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Pittsburgh, PA 15213. Phone: 412-623-6790; Fax: 412-623-1212; E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Why human tumors grow infiltrated by specific antitumor T cells has been a mystery attributed to negative factors released directly by the tumor or indirectly through immune intermediaries. The frequency and phenotype of myeloid-derived suppressor cells in the peripheral blood of melanoma patients and healthy donors are surprisingly similar. Clin Cancer Res; 18(19); 5157–9. ©2012 AACR.

Commentary on Gros et al., p. 5212

  • Received August 13, 2012.
  • Accepted August 16, 2012.

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